Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

Genetic studies of type 1 diabetes (T1D) have identified 50 susceptibility regions(1,2) (www.T1DBase.org) revealing major pathways contributing to risk(3), with some loci shared across immune disorders(4–6). In order to make genetic comparisons across autoimmune disorders as informative as possible...

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Detaylı Bibliyografya
Yayımlandı:Nat Genet
Asıl Yazarlar: Onengut-Gumuscu, Suna, Chen, Wei-Min, Burren, Oliver, Cooper, Nick J., Quinlan, Aaron R., Mychaleckyj, Josyf C., Farber, Emily, Bonnie, Jessica K., Szpak, Michal, Schofield, Ellen, Achuthan, Premanand, Guo, Hui, Fortune, Mary D., Stevens, Helen, Walker, Neil M., Ward, Luke D., Kundaje, Anshul, Kellis, Manolis, Daly, Mark J., Barrett, Jeffrey C., Cooper, Jason D., Deloukas, Panos, Todd, John A., Wallace, Chris, Concannon, Patrick, Rich, Stephen S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380767/
https://ncbi.nlm.nih.gov/pubmed/25751624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3245
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