Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis

Efficient clearance of apoptotic cells (efferocytosis) prevents inflammation and permits repair following tissue injury. Kidney injury molecule-1 (KIM-1) is a receptor for phosphatidylserine, an “eat-me” signal exposed on the surface of apoptotic cells that marks them for phagocytic clearance. KIM-1...

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Pubblicato in:Am J Physiol Renal Physiol
Autori principali: Gandhi, Rushi, Yi, James, Ha, Jihyen, Shi, Hang, Ismail, Ola, Nathoo, Sahra, Bonventre, Joseph V., Zhang, Xizhong, Gunaratnam, Lakshman
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380482/
https://ncbi.nlm.nih.gov/pubmed/24829508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00638.2013
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