Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma

Metastasis is present in approximately 30% of patients diagnosed with renal cell carcinoma (RCC) and is associated with a 5-year survival rate of < 15%. Kidney injury molecule 1 (KIM-1), encoded by the HAVCR1 gene, is a proximal tubule cell-surface glycoprotein and a biomarker for early detection...

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Udgivet i:Sci Rep
Main Authors: Lee, Jasper C., Yotis, Demitra M., Lee, Ji Yun, Sarabusky, Marie A., Shrum, Bradly, Champagne, Audrey, Ismail, Ola Z., Tutunea-Fatan, Elena, Leong, Hon S., Gunaratnam, Lakshman
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178330/
https://ncbi.nlm.nih.gov/pubmed/34088927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90919-8
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