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Methylation-Sensitive Expression of a DNA Demethylase Gene Serves As an Epigenetic Rheostat

Genomes must balance active suppression of transposable elements (TEs) with the need to maintain gene expression. In Arabidopsis, euchromatic TEs are targeted by RNA-directed DNA methylation (RdDM). Conversely, active DNA demethylation prevents accumulation of methylation at genes proximal to these...

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Vydáno v:PLoS Genet
Hlavní autoři: Williams, Ben P., Pignatta, Daniela, Henikoff, Steven, Gehring, Mary
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380477/
https://ncbi.nlm.nih.gov/pubmed/25826366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005142
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