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Methylation-Sensitive Expression of a DNA Demethylase Gene Serves As an Epigenetic Rheostat

Genomes must balance active suppression of transposable elements (TEs) with the need to maintain gene expression. In Arabidopsis, euchromatic TEs are targeted by RNA-directed DNA methylation (RdDM). Conversely, active DNA demethylation prevents accumulation of methylation at genes proximal to these...

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Publicado en:PLoS Genet
Main Authors: Williams, Ben P., Pignatta, Daniela, Henikoff, Steven, Gehring, Mary
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380477/
https://ncbi.nlm.nih.gov/pubmed/25826366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005142
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