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The Consensus 5' Splice Site Motif Inhibits mRNA Nuclear Export

In eukaryotes, mRNAs are synthesized in the nucleus and then exported to the cytoplasm where they are translated into proteins. We have mapped an element, which when present in the 3’terminal exon or in an unspliced mRNA, inhibits mRNA nuclear export. This element has the same sequence as the consen...

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Vydáno v:PLoS One
Hlavní autoři: Lee, Eliza S., Akef, Abdalla, Mahadevan, Kohila, Palazzo, Alexander F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380460/
https://ncbi.nlm.nih.gov/pubmed/25826302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122743
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