Activation of Checkpoint Kinase 2 Is Critical for Herpes Simplex Virus Type 1 Replication in Corneal Epithelium

BACKGROUND/AIMS: Herpes simplex virus (HSV) type I keratitis remains a leading cause of corneal morbidity, despite the availability of effective antiviral drugs. Improved understanding of virus-host interactions at the level of the host DNA damage response (DDR), a known factor in the development of...

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Bibliographic Details
Published in:Ophthalmic Res
Main Authors: Alekseev, Oleg, Limonnik, Vladimir, Donovan, Kelly, Azizkhan-Clifford, Jane
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380435/
https://ncbi.nlm.nih.gov/pubmed/25531207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000366228
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