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HSV-1 Hijacks the Host DNA Damage Response in Corneal Epithelial Cells through ICP4-Mediated Activation of ATM
PURPOSE: Herpes simplex virus type I (HSV-1) infection of corneal epithelial cells activates ataxia telangiectasia mutated (ATM), an apical kinase in the host DNA damage response pathway, whose activity is necessary for the progression of lytic HSV-1 infection. The purpose of this study is to invest...
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發表在: | Invest Ophthalmol Vis Sci |
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Main Authors: | , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
The Association for Research in Vision and Ophthalmology
2020
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415316/ https://ncbi.nlm.nih.gov/pubmed/32543665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.6.39 |
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