Selective and Genetic Constraints on Pneumococcal Serotype Switching

Streptococcus pneumoniae isolates typically express one of over 90 immunologically distinguishable polysaccharide capsules (serotypes), which can be classified into “serogroups” based on cross-reactivity with certain antibodies. Pneumococci can alter their serotype through recombinations affecting t...

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Publicat a:PLoS Genet
Autors principals: Croucher, Nicholas J., Kagedan, Lisa, Thompson, Claudette M., Parkhill, Julian, Bentley, Stephen D., Finkelstein, Jonathan A., Lipsitch, Marc, Hanage, William P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380333/
https://ncbi.nlm.nih.gov/pubmed/25826208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005095
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