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Retinoid X receptor α attenuates host antiviral response by suppressing type I interferon
The retinoid X receptor α (RXRα), a key nuclear receptor in metabolic processes, is down-regulated during host antiviral response. However, the roles of RXRα in host antiviral response are unknown. Here we show that RXRα overexpression or ligand activation increases host susceptibility to viral infe...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4380327/ https://ncbi.nlm.nih.gov/pubmed/25417649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6494 |
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