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Insight into Neutral and Disease-Associated Human Genetic Variants through Interpretable Predictors

A variety of methods that predict human nonsynonymous single nucleotide polymorphisms (SNPs) to be neutral or disease-associated have been developed over the last decade. These methods are used for pinpointing disease-associated variants in the many variants obtained with next-generation sequencing...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: van den Berg, Bastiaan A., Reinders, Marcel J. T., de Ridder, Dick, de Beer, Tjaart A. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380319/
https://ncbi.nlm.nih.gov/pubmed/25826299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120729
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