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Induction of tumor initiation is dependent on CD44s in c-Met(+) hepatocellular carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) patients with active hepatocyte growth factor (HGF)/c-Met signaling have a significantly worse prognosis. c-Met, a high affinity receptor for HGF, plays a critical role in cancer growth, invasion and metastasis. c-Met and CD44 have been utilized as cell sur...
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Publicado no: | BMC Cancer |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4380258/ https://ncbi.nlm.nih.gov/pubmed/25886575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1166-4 |
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