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Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics

BACKGROUND: Tumor initiating stem-like cells (TISCs) are a subset of neoplastic cells that possess distinct survival mechanisms and self-renewal characteristics crucial for tumor maintenance and propagation. The induction of epithelial-mesenchymal-transition (EMT) by TGFβ has been recently linked to...

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Detalhes bibliográficos
Main Authors: Dang, Hien, Ding, Wei, Emerson, Dow, Rountree, C Bart
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189192/
https://ncbi.nlm.nih.gov/pubmed/21929801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-396
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