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Spirotetronate Polyketides as Leads in Drug Discovery

[Image: see text] The discovery of chlorothricin (1) defined a new family of microbial metabolites with potent antitumor antibiotic properties collectively referred to as spirotetronate polyketides. These microbial metabolites are structurally distinguished by the presence of a spirotetronate motif...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Lacoske, Michelle H., Theodorakis, Emmanuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society and American Society of Pharmacognosy 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380204/
https://ncbi.nlm.nih.gov/pubmed/25434976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500757w
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