P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation

Purinergic 2X7 receptor (P2X7R) and nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) are expressed in macrophages in atherosclerotic lesions. However, the mechanisms through which P2X7R participates in the inflammatory response in atherosclerosis remain largely unknown. The...

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Veröffentlicht in:Int J Mol Med
Hauptverfasser: PENG, KUANG, LIU, LUSHAN, WEI, DANGHENG, LV, YUNCHENG, WANG, GANG, XIONG, WENHAO, WANG, XIAOQING, ALTAF, AFRASYAB, WANG, LILI, HE, DAN, WANG, HONGYAN, QU, PENG
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380202/
https://ncbi.nlm.nih.gov/pubmed/25761252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2129
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