Cytotoxic Activity of Rearranged Drimane Meroterpenoids against Colon Cancer Cells via Down-Regulation of β-Catenin Expression

[Image: see text] Colorectal cancer has emerged as a major cause of death in Western countries. Down-regulation of β-catenin expression has been considered a promising approach for cytotoxic drug formulation. Eight 4,9-friedodrimane-type sesquiterpenoids (1–8) were acquired using the oxidative poten...

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Pubblicato in:J Nat Prod
Autori principali: Hwang, In Hyun, Oh, Joonseok, Zhou, Wei, Park, Seoyoung, Kim, Joo-Hyun, Chittiboyina, Amar G., Ferreira, Daneel, Song, Gyu Yong, Oh, Sangtaek, Na, MinKyun, Hamann, Mark T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society and American Society of Pharmacognosy 2015
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380199/
https://ncbi.nlm.nih.gov/pubmed/25590830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500843m
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