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The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins.

Apolipoprotein E (apoE) is hypothesized to mediate lipoprotein clearance by binding to two receptors: (i) the low density lipoprotein receptor (LDLR) and (ii) a chylomicron remnant receptor. To test this hypothesis, we have compared plasma lipoproteins in mice that are homozygous for targeted disrup...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Principais autores: Ishibashi, S, Herz, J, Maeda, N, Goldstein, J L, Brown, M S
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 1994
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8183926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.10.4431
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