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Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect?
Increasing evidence suggests that selective neuronal loss in neurodegenerative diseases involves activation of cysteine aspartyl proteases (caspases), which initiate and execute apoptosis. In Alzheimer disease both extracellular amyloid deposits and intracellular amyloid β protein may activate caspa...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC437977/ https://ncbi.nlm.nih.gov/pubmed/15232608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422317 |
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