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The multivesicular body is the major internal site of prion conversion
The conversion of the properly folded prion protein, PrPc, to its misfolded amyloid form, PrPsc, occurs as the two proteins traffic along the endocytic pathway and PrPc is exposed to PrPsc. To determine the specific site of prion conversion, we knocked down various proteins in the endocytic pathway...
Gorde:
| Argitaratua izan da: | J Cell Sci |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Company of Biologists
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4379730/ https://ncbi.nlm.nih.gov/pubmed/25663703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.165472 |
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