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Autophagosome dynamics in neurodegeneration at a glance
Autophagy is an essential homeostatic process for degrading cellular cargo. Aging organelles and protein aggregates are degraded by the autophagosome-lysosome pathway, which is particularly crucial in neurons. There is increasing evidence implicating defective autophagy in neurodegenerative diseases...
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| Publicado en: | J Cell Sci |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Company of Biologists
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4379723/ https://ncbi.nlm.nih.gov/pubmed/25829512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.161216 |
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