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Autophagosome dynamics in neurodegeneration at a glance

Autophagy is an essential homeostatic process for degrading cellular cargo. Aging organelles and protein aggregates are degraded by the autophagosome-lysosome pathway, which is particularly crucial in neurons. There is increasing evidence implicating defective autophagy in neurodegenerative diseases...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Wong, Yvette C., Holzbaur, Erika L. F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379723/
https://ncbi.nlm.nih.gov/pubmed/25829512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.161216
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