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Protein derivatization and sequential ion/ion reactions to enhance sequence coverage produced by electron transfer dissociation mass spectrometry
Previously, we described implementation of a front-end ETD (electron transfer dissociation) source for an Orbitrap instrument (1). This source facilitates multiple fills of the C-trap with product ions from ETD of intact proteins prior to mass analysis. The result is a dramatic enhancement of the ob...
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| Udgivet i: | Int J Mass Spectrom |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4379715/ https://ncbi.nlm.nih.gov/pubmed/25844056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2014.06.023 |
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