Protein derivatization and sequential ion/ion reactions to enhance sequence coverage produced by electron transfer dissociation mass spectrometry

Previously, we described implementation of a front-end ETD (electron transfer dissociation) source for an Orbitrap instrument (1). This source facilitates multiple fills of the C-trap with product ions from ETD of intact proteins prior to mass analysis. The result is a dramatic enhancement of the ob...

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Vydáno v:Int J Mass Spectrom
Hlavní autoři: Anderson, Lissa C., English, A. Michelle, Wang, Weihan, Bai, Dina L., Shabanowitz, Jeffrey, Hunt, Donald F
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379715/
https://ncbi.nlm.nih.gov/pubmed/25844056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2014.06.023
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