Dose-Dependent Dual Role of PIT-1 (POU1F1) in Somatolactotroph Cell Proliferation and Apoptosis

To test the role of wtPIT-1 (PITWT) or PIT-1 (R271W) (PIT271) in somatolactotroph cells, we established, using inducible lentiviral vectors, sublines of GH4C1 somatotroph cells that allow the blockade of the expression of endogenous PIT-1 and/or the expression of PITWT or PIT271, a dominant negative...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Jullien, Nicolas, Roche, Catherine, Brue, Thierry, Figarella-Branger, Dominique, Graillon, Thomas, Barlier, Anne, Herman, Jean-Paul
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379079/
https://ncbi.nlm.nih.gov/pubmed/25822178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120010
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker