Dose-Dependent Dual Role of PIT-1 (POU1F1) in Somatolactotroph Cell Proliferation and Apoptosis

To test the role of wtPIT-1 (PITWT) or PIT-1 (R271W) (PIT271) in somatolactotroph cells, we established, using inducible lentiviral vectors, sublines of GH4C1 somatotroph cells that allow the blockade of the expression of endogenous PIT-1 and/or the expression of PITWT or PIT271, a dominant negative...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Jullien, Nicolas, Roche, Catherine, Brue, Thierry, Figarella-Branger, Dominique, Graillon, Thomas, Barlier, Anne, Herman, Jean-Paul
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379079/
https://ncbi.nlm.nih.gov/pubmed/25822178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120010
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