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Thyroxine Differentially Modulates the Peripheral Clock: Lessons from the Human Hair Follicle

The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation. Similarly, thyroid hormones prolong anagen and stimulate pigmentation in cultured human HFs. In addition they are recog...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hardman, Jonathan A., Haslam, Iain S., Farjo, Nilofer, Farjo, Bessam, Paus, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379003/
https://ncbi.nlm.nih.gov/pubmed/25822259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121878
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