Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles

Hair growth disorders often carry a major psychological burden. Therefore, more effective human hair growth–modulatory agents urgently need to be developed. Here, we used the hypertrichosis-inducing immunosuppressant, Cyclosporine A (CsA), as a lead compound to identify new hair growth–promoting mol...

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Bibliografiske detaljer
Udgivet i:PLoS Biol
Main Authors: Hawkshaw, Nathan J., Hardman, Jonathan A., Haslam, Iain S., Shahmalak, Asim, Gilhar, Amos, Lim, Xinhong, Paus, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Short Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940179/
https://ncbi.nlm.nih.gov/pubmed/29738529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2003705
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