Comparison of Newly Diagnosed and Relapsed Patients with Acute Promyelocytic Leukemia Treated with Arsenic Trioxide: Insight into Mechanisms of Resistance

There is limited data on the clinical, cellular and molecular changes in relapsed acute promyeloytic leukemia (RAPL) in comparison with newly diagnosed cases (NAPL). We undertook a prospective study to compare NAPL and RAPL patients treated with arsenic trioxide (ATO) based regimens. 98 NAPL and 28...

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Publicado en:PLoS One
Autores principales: Chendamarai, Ezhilarasi, Ganesan, Saravanan, Alex, Ansu Abu, Kamath, Vandana, Nair, Sukesh C., Nellickal, Arun Jose, Janet, Nancy Beryl, Srivastava, Vivi, Lakshmi, Kavitha M., Viswabandya, Auro, Abraham, Aby, Aiyaz, Mohammed, Mullapudi, Nandita, Mugasimangalam, Raja, Padua, Rose Ann, Chomienne, Christine, Chandy, Mammen, Srivastava, Alok, George, Biju, Balasubramanian, Poonkuzhali, Mathews, Vikram
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378855/
https://ncbi.nlm.nih.gov/pubmed/25822503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121912
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