Comparison of Newly Diagnosed and Relapsed Patients with Acute Promyelocytic Leukemia Treated with Arsenic Trioxide: Insight into Mechanisms of Resistance

There is limited data on the clinical, cellular and molecular changes in relapsed acute promyeloytic leukemia (RAPL) in comparison with newly diagnosed cases (NAPL). We undertook a prospective study to compare NAPL and RAPL patients treated with arsenic trioxide (ATO) based regimens. 98 NAPL and 28...

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Udgivet i:PLoS One
Main Authors: Chendamarai, Ezhilarasi, Ganesan, Saravanan, Alex, Ansu Abu, Kamath, Vandana, Nair, Sukesh C., Nellickal, Arun Jose, Janet, Nancy Beryl, Srivastava, Vivi, Lakshmi, Kavitha M., Viswabandya, Auro, Abraham, Aby, Aiyaz, Mohammed, Mullapudi, Nandita, Mugasimangalam, Raja, Padua, Rose Ann, Chomienne, Christine, Chandy, Mammen, Srivastava, Alok, George, Biju, Balasubramanian, Poonkuzhali, Mathews, Vikram
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378855/
https://ncbi.nlm.nih.gov/pubmed/25822503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121912
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