Comparison of Newly Diagnosed and Relapsed Patients with Acute Promyelocytic Leukemia Treated with Arsenic Trioxide: Insight into Mechanisms of Resistance

There is limited data on the clinical, cellular and molecular changes in relapsed acute promyeloytic leukemia (RAPL) in comparison with newly diagnosed cases (NAPL). We undertook a prospective study to compare NAPL and RAPL patients treated with arsenic trioxide (ATO) based regimens. 98 NAPL and 28...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Chendamarai, Ezhilarasi, Ganesan, Saravanan, Alex, Ansu Abu, Kamath, Vandana, Nair, Sukesh C., Nellickal, Arun Jose, Janet, Nancy Beryl, Srivastava, Vivi, Lakshmi, Kavitha M., Viswabandya, Auro, Abraham, Aby, Aiyaz, Mohammed, Mullapudi, Nandita, Mugasimangalam, Raja, Padua, Rose Ann, Chomienne, Christine, Chandy, Mammen, Srivastava, Alok, George, Biju, Balasubramanian, Poonkuzhali, Mathews, Vikram
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378855/
https://ncbi.nlm.nih.gov/pubmed/25822503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121912
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