Reliable cell cycle commitment in budding yeast is ensured by signal integration

Cell fate decisions are critical for life, yet little is known about how their reliability is achieved when signals are noisy and fluctuating with time. In this study, we show that in budding yeast, the decision of cell cycle commitment (Start) is determined by the time integration of its triggering...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Liu, Xili, Wang, Xin, Yang, Xiaojing, Liu, Sen, Jiang, Lingli, Qu, Yimiao, Hu, Lufeng, Ouyang, Qi, Tang, Chao
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378612/
https://ncbi.nlm.nih.gov/pubmed/25590650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03977
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