WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals

Development of the metanephric kidney depends on tightly regulated interplay between self-renewal and differentiation of a nephron progenitor cell (NPC) pool. Several key factors required for the survival of NPCs have been identified, including fibroblast growth factor (FGF) signaling and the transc...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Kann, Martin, Bae, Eunnyung, Lenz, Maximilian O., Li, Liangji, Trannguyen, BaoTran, Schumacher, Valerie A., Taglienti, Mary E., Bordeianou, Liliana, Hartwig, Sunny, Rinschen, Markus M., Schermer, Bernhard, Benzing, Thomas, Fan, Chen-Ming, Kreidberg, Jordan A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378252/
https://ncbi.nlm.nih.gov/pubmed/25804736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.119735
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