Activation of Protein Kinase C-α and Src Kinase Increases Urea Transporter A1 α-2, 6 Sialylation

The urea transporter A1 (UT-A1) is a glycosylated protein with two glycoforms: 117 and 97 kD. In diabetes, the increased abundance of the heavily glycosylated 117-kD UT-A1 corresponds to an increase of kidney tubule urea permeability. We previously reported that diabetes not only causes an increase...

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Bibliografische gegevens
Gepubliceerd in:J Am Soc Nephrol
Hoofdauteurs: Li, Xuechen, Yang, Baoxue, Chen, Minguang, Klein, Janet D., Sands, Jeff M., Chen, Guangping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Nephrology 2015
Onderwerpen:
Basic Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378103/
https://ncbi.nlm.nih.gov/pubmed/25300290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014010026
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