Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy

BACKGROUND: While large-scale cancer genomic projects are comprehensively characterizing the mutational spectrum of various cancers, so far little attention has been devoted to either define the antigenicity of these mutations or to characterize the immune responses they elicit. Here we present a st...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Angelova, Mihaela, Charoentong, Pornpimol, Hackl, Hubert, Fischer, Maria L, Snajder, Rene, Krogsdam, Anne M, Waldner, Maximilian J, Bindea, Gabriela, Mlecnik, Bernhard, Galon, Jerome, Trajanoski, Zlatko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377852/
https://ncbi.nlm.nih.gov/pubmed/25853550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0620-6
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