Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy

BACKGROUND: While large-scale cancer genomic projects are comprehensively characterizing the mutational spectrum of various cancers, so far little attention has been devoted to either define the antigenicity of these mutations or to characterize the immune responses they elicit. Here we present a st...

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Dades bibliogràfiques
Publicat a:Genome Biol
Autors principals: Angelova, Mihaela, Charoentong, Pornpimol, Hackl, Hubert, Fischer, Maria L, Snajder, Rene, Krogsdam, Anne M, Waldner, Maximilian J, Bindea, Gabriela, Mlecnik, Bernhard, Galon, Jerome, Trajanoski, Zlatko
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377852/
https://ncbi.nlm.nih.gov/pubmed/25853550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0620-6
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