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A severe phenotype of Gitelman syndrome with increased prostaglandin excretion and favorable response to indomethacin

Our understanding of Gitelman syndrome (GS) and Bartter syndrome has continued to evolve with the use of genetic testing to more precisely define the tubular defects responsible. GS is caused by mutations in the SLC12A3 gene encoding the Na(+)–Cl(−) co-transporter of the distal convoluted tubule (NC...

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Détails bibliographiques
Publié dans:Clin Kidney J
Auteurs principaux: Larkins, Nicholas, Wallis, Mathew, McGillivray, Barbara, Mammen, Cherry
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377751/
https://ncbi.nlm.nih.gov/pubmed/25852896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfu029
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