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A severe phenotype of Gitelman syndrome with increased prostaglandin excretion and favorable response to indomethacin

Our understanding of Gitelman syndrome (GS) and Bartter syndrome has continued to evolve with the use of genetic testing to more precisely define the tubular defects responsible. GS is caused by mutations in the SLC12A3 gene encoding the Na(+)–Cl(−) co-transporter of the distal convoluted tubule (NC...

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Publicat a:Clin Kidney J
Autors principals: Larkins, Nicholas, Wallis, Mathew, McGillivray, Barbara, Mammen, Cherry
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377751/
https://ncbi.nlm.nih.gov/pubmed/25852896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfu029
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