A novel PKD2L1 C-terminal domain critical for trimerization and channel function

As a transient receptor potential (TRP) superfamily member, polycystic kidney disease 2-like-1 (PKD2L1) is also called TRPP3 and has similar membrane topology as voltage-gated cation channels. PKD2L1 is involved in hedgehog signaling, intestinal development, and sour tasting. PKD2L1 and PKD1L3 form...

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Publicado no:Sci Rep
Main Authors: Zheng, Wang, Hussein, Shaimaa, Yang, JungWoo, Huang, Jun, Zhang, Fan, Hernandez-Anzaldo, Samuel, Fernandez-Patron, Carlos, Cao, Ying, Zeng, Hongbo, Tang, Jingfeng, Chen, Xing-Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377555/
https://ncbi.nlm.nih.gov/pubmed/25820328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09460
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