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Genetic alterations of protein tyrosine phosphatases in human cancers

Protein tyrosine phosphatases (PTPs) are enzymes that remove phosphate from tyrosine residues in proteins. Recent whole-exome sequencing of human cancer genomes reveals that many PTPs are frequently mutated in a variety of cancers. Among these mutated PTPs, protein tyrosine phosphatase T (PTPRT) app...

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Publicat a:Oncogene
Autors principals: Zhao, Shuliang, Sedwick, David, Wang, Zhenghe
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377308/
https://ncbi.nlm.nih.gov/pubmed/25263441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.326
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