Mesenchymal Stromal Cells: Inhibiting PDGF Receptors or Depleting Fibronectin Induces Mesodermal Progenitors with Endothelial Potential

Realizing the full therapeutic potential of mesenchymal stromal/stem cells (MSCs) awaits improved understanding of mechanisms controlling their fate. Using MSCs cultured as spheroids to recapitulate a three-dimensional cellular environment, we show that perturbing the mesenchymal regulators, platele...

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Bibliografiska uppgifter
I publikationen:Stem Cells
Huvudupphovsmän: Ball, S G, Worthington, J J, Canfield, A E, Merry, C L R, Kielty, C M
Materialtyp: Artigo
Språk:Inglês
Publicerad: BlackWell Publishing Ltd 2014
Ämnen:
Tissue-Specific Stem Cells
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377076/
https://ncbi.nlm.nih.gov/pubmed/24022915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1538
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