Mesenchymal Stromal Cells: Inhibiting PDGF Receptors or Depleting Fibronectin Induces Mesodermal Progenitors with Endothelial Potential

Realizing the full therapeutic potential of mesenchymal stromal/stem cells (MSCs) awaits improved understanding of mechanisms controlling their fate. Using MSCs cultured as spheroids to recapitulate a three-dimensional cellular environment, we show that perturbing the mesenchymal regulators, platele...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Ball, S G, Worthington, J J, Canfield, A E, Merry, C L R, Kielty, C M
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Tissue-Specific Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377076/
https://ncbi.nlm.nih.gov/pubmed/24022915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1538
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