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Characterization of Dedifferentiating Human Mature Adipocytes from the Visceral and Subcutaneous Fat Compartments: Fibroblast-Activation Protein Alpha and Dipeptidyl Peptidase 4 as Major Components of Matrix Remodeling

Mature adipocytes can reverse their phenotype to become fibroblast-like cells. This is achieved by ceiling culture and the resulting cells, called dedifferentiated fat (DFAT) cells, are multipotent. Beyond the potential value of these cells for regenerative medicine, the dedifferentiation process it...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Lessard, Julie, Pelletier, Mélissa, Biertho, Laurent, Biron, Simon, Marceau, Simon, Hould, Frédéric-Simon, Lebel, Stéfane, Moustarah, Fady, Lescelleur, Odette, Marceau, Picard, Tchernof, André
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376729/
https://ncbi.nlm.nih.gov/pubmed/25816202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122065
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