Characterization of Dedifferentiating Human Mature Adipocytes from the Visceral and Subcutaneous Fat Compartments: Fibroblast-Activation Protein Alpha and Dipeptidyl Peptidase 4 as Major Components of Matrix Remodeling

Mature adipocytes can reverse their phenotype to become fibroblast-like cells. This is achieved by ceiling culture and the resulting cells, called dedifferentiated fat (DFAT) cells, are multipotent. Beyond the potential value of these cells for regenerative medicine, the dedifferentiation process it...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lessard, Julie, Pelletier, Mélissa, Biertho, Laurent, Biron, Simon, Marceau, Simon, Hould, Frédéric-Simon, Lebel, Stéfane, Moustarah, Fady, Lescelleur, Odette, Marceau, Picard, Tchernof, André
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376729/
https://ncbi.nlm.nih.gov/pubmed/25816202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122065
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