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Actin-Mediated Gene Expression Depends on RhoA and Rac1 Signaling in Proximal Tubular Epithelial Cells
Morphological alterations of cells can lead to modulation of gene expression. An essential link is the MKL1-dependent activation of serum response factor (SRF), which translates changes in the ratio of G- and F-actin into mRNA transcription. SRF activation is only partially characterized in non-tran...
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出版年: | PLoS One |
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主要な著者: | , , , |
フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376694/ https://ncbi.nlm.nih.gov/pubmed/25816094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121589 |
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