Decreased HIV-Specific T-Regulatory Responses Are Associated with Effective DC-Vaccine Induced Immunity

The role of regulatory T cells (Tregs) in vaccination has been poorly investigated. We have reported that vaccination with ex vivo-generated dendritic-cells (DC) loaded with HIV-lipopeptides (LIPO-5-DC vaccine) in HIV-infected patients was well tolerated and highly immunogenic. These responses and t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Brezar, Vedran, Ruffin, Nicolas, Richert, Laura, Surenaud, Mathieu, Lacabaratz, Christine, Palucka, Karolina, Thiébaut, Rodolphe, Banchereau, Jacques, Levy, Yves, Seddiki, Nabila
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376642/
https://ncbi.nlm.nih.gov/pubmed/25816350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004752
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