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Negative modulation of suppressive HIV-specific regulatory T cells by IL-2 adjuvanted therapeutic vaccine

The potential benefit in using IL-2 in immunotherapy for cancer and autoimmunity has been linked to the modulation of immune responses, which partly relies on a direct effect on Tregs populations. Here, we revisited the role of IL-2 in HIV infection and investigated whether its use as an adjuvant wi...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Autores principales: Brezar, Vedran, Hani, Lylia, Surenaud, Mathieu, Hubert, Audrey, Lacabaratz, Christine, Lelièvre, Jean-Daniel, Levy, Yves, Seddiki, Nabila
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529021/
https://ncbi.nlm.nih.gov/pubmed/28708863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006489
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