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Endothelial PPARγ Protects Against Vascular Thrombosis by Downregulating P-Selectin Expression
OBJECTIVE: We tested the hypothesis that endothelial proliferator-activated receptor-gamma (PPARγ) protects against vascular thrombosis using a transgenic mouse model expressing a PPARγ mutant (E-V290M) selectively in endothelium. APPROACH AND RESULTS: The time to occlusive thrombosis of the carotid...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376629/ https://ncbi.nlm.nih.gov/pubmed/25675995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305378 |
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