A single nucleotide polymorphism in osteonectin 3’ untranslated region regulates bone volume and is targeted by miR-433

Osteonectin/SPARC is one of the most abundant non-collagenous extracellular matrix proteins in bone, regulating collagen fiber assembly and promoting osteoblast differentiation. Osteonectin-null and –haploinsufficient mice have low turnover osteopenia, indicating that osteonectin contributes to norm...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Bone Miner Res
Hlavní autoři: Dole, Neha S., Kapinas, Kristina, Kessler, Catherine B., Yee, Siu-Pok, Adams, Douglas J., Pereira, Renata C., Delany, Anne M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376624/
https://ncbi.nlm.nih.gov/pubmed/25262637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2378
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky