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A single nucleotide polymorphism in osteonectin 3’ untranslated region regulates bone volume and is targeted by miR-433
Osteonectin/SPARC is one of the most abundant non-collagenous extracellular matrix proteins in bone, regulating collagen fiber assembly and promoting osteoblast differentiation. Osteonectin-null and –haploinsufficient mice have low turnover osteopenia, indicating that osteonectin contributes to norm...
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| Publicat a: | J Bone Miner Res |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376624/ https://ncbi.nlm.nih.gov/pubmed/25262637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2378 |
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