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A single nucleotide polymorphism in osteonectin 3’ untranslated region regulates bone volume and is targeted by miR-433
Osteonectin/SPARC is one of the most abundant non-collagenous extracellular matrix proteins in bone, regulating collagen fiber assembly and promoting osteoblast differentiation. Osteonectin-null and –haploinsufficient mice have low turnover osteopenia, indicating that osteonectin contributes to norm...
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Publicado no: | J Bone Miner Res |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376624/ https://ncbi.nlm.nih.gov/pubmed/25262637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2378 |
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