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Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression
Arsenic trioxide (As(2)O(3)) is commonly used to treat acute promyelocytic leukemia and solid tumors. However, the clinical application of the agent is limited by its cyto- and genotoxic effects on normal cells. Thus, relief of As(2)O(3) toxicity in normal cells is essentially necessary for improvem...
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| Publicado no: | Environ Mol Mutagen |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376608/ https://ncbi.nlm.nih.gov/pubmed/25339131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21919 |
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