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Protection of Nrf2 against arsenite-induced oxidative damage is regulated by the cyclic guanosine monophosphate-protein kinase G signaling pathway

Arsenite has been shown to induce a variety of oxidative damage in mammalian cells. However, the mechanisms underlying cellular responses to its adverse effects remain unknown. We previously showed that the level of Nrf2, a nuclear transcription factor significantly increased in arsenite-treated hum...

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Detalhes bibliográficos
Publicado no:Environ Toxicol
Main Authors: Chen, Chengzhi, Jiang, Xuejun, Gu, Shiyan, Lai, Yanhao, Liu, Yuan, Zhang, Zunzhen
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403658/
https://ncbi.nlm.nih.gov/pubmed/27774770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/tox.22374
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